You, Qidong : rechercher sur Z-Library

European Journal of Drug Metabolism and Pharmacokinetics

Année:

2017

Langue:

english

Fichier:

PDF, 993 KB

english, 2017

Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes

Tingting Li, Ning Li, Qinglong Guo, Hui Ji, Di Zhao, Shan Xie, Xiaonan Li, Zhixia Qiu, Deen Han, Xijing Chen, Qidong You

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 334 KB

english, 2011

Subchronic toxicity and plasma pharmacokinetic studies on wogonin, a natural flavonoid, in Beagle dogs

Jian Peng, Qi Qi, Qidong You, Rong Hu, Wenyuan Liu, Feng Feng, Guangji Wang, Qinglong Guo

Journal:

Journal of Ethnopharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 307 KB

english, 2009

Baicalein inhibits angiogenesis induced by lipopolysaccharide through TRAF6 mediated toll-like receptor 4 pathway

Yun Ling, Ling Wang, Yan Chen, Feng Feng, Qidong You, Na Lu, Qinglong Guo

Journal:

Biomedicine & Preventive Nutrition

Année:

2011

Langue:

english

Fichier:

PDF, 654 KB

english, 2011

Quaternary Climate Change and the Formation of River Terraces across Growing Anticlines on the North Flank of the Tien Shan, China

Peter Molnar, Erik Thorson Brown, B. Clark Burchfiel, Qidong Deng, Xianyue Feng, Jun Li, Grant M. Raisbeck, Jianbang Shi, Wu Zhangming, Françoise Yiou and Huichuan You

Journal:

The Journal of Geology

Année:

1994

Langue:

english

Fichier:

PDF, 4.47 MB

english, 1994

Synthesis, SAR and Biological Evaluation of Natural and Non-natural Hydroxylated and Prenylated Xanthones as Antitumor Agents

Zhang, Xiaojin, Li, Xiang, Ye, Suofu, Zhang, Yu, Tao, Lei, Gao, Yuan, Gong, Dandan, Xi, Meiyang, Meng, Huyan, Zhang, Mingqian, Gao, Wenlei, Xu, Xiaoli, Guo, Qinglong, You, Qidong

Journal:

Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 437 KB

english, 2012

Prodrug strategy for cancer cell-specific targeting: A recent overview

Zhang, Xian, Li, Xiang, You, Qidong, Zhang, Xiaojin

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2017

Discovery of a Keap1-dependent peptide PROTAC to knockdown Tau by ubiquitination-proteasome degradation pathway

Lu, Mengchen, Liu, Tian, Jiao, Qiong, Ji, Jianai, Tao, Mengmin, Liu, Yijun, You, Qidong, Jiang, Zhengyu

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.75 MB

english, 2018

An NAD(P)H:Quinone Oxidoreductase 1 Responsive and Self-Immolative Prodrug of 5-Fluorouracil for Safe and Effective Cancer Therapy

Zhang, Xian, Li, Xiang, Li, Zhihong, Wu, Xingsen, Wu, Yue, You, Qidong, Zhang, Xiaojin

Journal:

Organic Letters

Année:

2018

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2018

Structure-guided design and synthesis of isoflavone analogs of GW4064 with potent lipid accumulation inhibitory activities

Qiu, Rongmao, Luo, Guoshun, Cai, Xuerong, Liu, Linyi, Chen, Mingqi, Chen, Deying, You, Qidong, Xiang, Hua

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2018

ChemInform Abstract: Use of Polyphosphoric Acid in the Hydrolysis of Chromone Esters.

Xungui He, Zhiyu Li, Qidong You

Journal:

Année:

2002

Fichier:

PDF, 26 KB

2002

A Novel Bicyclic Ketolide Derivative.

Ying Zhao, Qidong You, Wenbin Shen

Journal:

Année:

2003

Fichier:

PDF, 64 KB

2003

ChemInform Abstract: A General and Efficient Synthesis of 2-Substituted Oxazolopyridines.

Dan Xu, Xianfang Xu, Zongliang Liu, Li-Ping Sun, Qidong You

Journal:

Année:

2009

Fichier:

PDF, 30 KB

2009

ChemInform Abstract: Design, Synthesis and Evaluation of Tetrahydroisoquinolines as New Kinesin Spindle Protein Inhibitors.

Cheng Jiang, Qidong You, Fei Liu, Wutong Wu, Qinglong Guo, Jiwang Chern, Lei Yang, Mengling Chen

Journal:

Année:

2009

Fichier:

PDF, 28 KB

2009

ChemInform Abstract: Spectacular Modification of Gambogic Acid on Microwave Irradiation in Methanol: Isolation and Structure Identification of Two Products with Potent Antitumor Activity.

Xiaojian Wang, Na Lu, Qian Yang, Qinsheng Dai, Lei Tao, Xiaoke Guo, Qinglong Guo, Qidong You

Journal:

Chinese Journal of Chemistry

Année:

2010

Fichier:

PDF, 20 KB

2010

Pharmacophore Identification of Hydroxamate HDAC 1 Inhibitors

Liqin YU, Fei LIU, Yadong CHEN, Qidong YOU

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 185 KB

english, 2009

Synthesis and Anti-tumor Evaluation of B-ring Modified Caged Xanthone Analogues of Gambogic Acid

Xiang Li, Xiaojin Zhang, Xiaojian Wang, Nianguang Li, Changjun Lin, Yuan Gao, Zhuoqin Yu, Qinglong Guo, Qidong You

Journal:

Chinese Journal of Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 420 KB

english, 2012

Pharmacophore Modeling and in Silico Screening Studies to Design Potential KDR Kinase Inhibitors

Dan Xu, Haopeng Sun, Yadong Chen, Liping Sun, Prof. Dr. Qidong You

Journal:

Chinese Journal of Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 177 KB

english, 2011

Structure-Based Virtual Screening and Electrophysiological Evaluation of New Chemotypes of Kv1.5 Channel Blockers

Qian Yang, David Fedida, Hongjian Xu, Binghe Wang, Lupei Du, Xiaojian Wang, Minyong Li, Qidong You

Journal:

ChemMedChem

Année:

2010

Langue:

english

Fichier:

PDF, 492 KB

english, 2010

Different apoptotic effects of wogonin via induction of H2O2 generation and Ca2+ overload in malignant hepatoma and normal hepatic cells

Libin Wei, Na Lu, Qinsheng Dai, Jingjing Rong, Yan Chen, Zhiyu Li, Qidong You, Qinglong Guo

Journal:

Journal of Cellular Biochemistry

Année:

2010

Langue:

english

Fichier:

PDF, 2.55 MB

english, 2010

Involvement of p53 in oroxylin A-induced apoptosis in cancer cells

Rong Mu, Qi Qi, Hongyan Gu, Jia Wang, Yong Yang, Jingjing Rong, Wei Liu, Na Lu, Qidong You, Qinglong Guo

Journal:

Molecular Carcinogenesis

Année:

2009

Langue:

english

Fichier:

PDF, 485 KB

english, 2009

Design, synthesis and biological evaluation of novel compounds with conjugated structure as anti-tumor agents

Hong Su, Angela Nebbioso, Vincenzo Carafa, Yadong Chen, Bo Yang, Lucia Altucci, Qidong You

Journal:

Bioorganic & Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 848 KB

english, 2008

Synthesis and local anesthetic activity of fluoro-substituted imipramine and its analogues

Wen Li, Qidong You

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 113 KB

english, 2007

Novel hexacyclic camptothecin derivatives. Part 1: Synthesis and cytotoxicity of camptothecins with an A-ring fused 1,3-oxazine ring

Sheng Wang, Yuyan Li, Yonghui Liu, Aijun Lu, Qidong You

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 158 KB

english, 2008

Design and synthesis of N-methylmaleimide indolocarbazole bearing modified 2-acetamino acid moieties as Topoisomerase I inhibitors

Zhiyu Li, Fuming Zhai, Li Zhao, Qinglong Guo, Qidong You

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 305 KB

english, 2009

Molecular hybridization, synthesis, and biological evaluation of novel chroman IKr and IKs dual blockers

Lupei Du, Minyong Li, Qian Yang, Yiqun Tang, Qidong You, Lin Xia

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 574 KB

english, 2009

Novel N-hydroxybenzamide-based HDAC inhibitors with branched CAP group

Hong Su, Liqin Yu, Angela Nebbioso, Vincenzo Carafa, Yadong Chen, Lucia Altucci, Qidong You

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 322 KB

english, 2009

Spectacular modification of Gambogic acid on microwave irradiation in methanol: Isolation and structure identification of two products with potent anti-tumor activity

Xiaojian Wang, Na Lu, Qian Yang, Qinsheng Dai, Lei Tao, Xiaoke Guo, Qinglong Guo, Qidong You

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.79 MB

english, 2010

Studies on chemical structure modification and biology of a natural product, Gambogic acid (I): Synthesis and biological evaluation of oxidized analogues of gambogic acid

Jinxin Wang, Li Zhao, Yang Hu, Qinglong Guo, Lei Zhang, Xiaojian Wang, Nianguang Li, Qidong You

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 650 KB

english, 2009

3D-QSAR studies of HDACs inhibitors using pharmacophore-based alignment

Yadong Chen, Huifang Li, Wanquan Tang, Chengchao Zhu, Yongjun Jiang, Jianwei Zou, Qingsen Yu, Qidong You

Journal:

Journal of Molecular Graphics and Modelling

Année:

2009

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2009

Modeling the binding modes of Kv1.5 potassium channel and blockers

Qian Yang, Lupei Du, Xiaojian Wang, Minyong Li, Qidong You

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 2.85 MB

english, 2008

Wogonoside inhibits lipopolysaccharide-induced angiogenesis in vitro and in vivo via toll-like receptor 4 signal transduction

Yan Chen, Na Lu, Yun Ling, Ying Gao, Ling Wang, Yu Sun, Qi Qi, Feng Feng, Wenyuan Liu, Wei Liu, Qidong You, Qinglong Guo

Journal:

Toxicology

Année:

2009

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2009

Reactive oxygen species accumulation contributes to gambogic acid-induced apoptosis in human hepatoma SMMC-7721 cells

Feifei Nie, Xiaonan Zhang, Qi Qi, Lan Yang, Yong Yang, Wei Liu, Na Lu, Zhaoqiu Wu, Qidong You, Qinglong Guo

Journal:

Toxicology

Année:

2009

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2009

Inhibitory effects of wogonin on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-9

Pu Chen, Na Lu, Yun Ling, Yan Chen, Hui Hui, Zhijian Lu, Xiuming Song, Zhiyu Li, Qidong You, Qinglong Guo

Journal:

Toxicology

Année:

2011

Langue:

english

Fichier:

PDF, 916 KB

english, 2011

A novel bicyclic ketolide derivative

Ying Zhao, Qidong You, Wenbin Shen

Journal:

Journal of Cancer Research and Clinical Oncology

Année:

2003

Langue:

english

Fichier:

PDF, 157 KB

english, 2003

Toxicological studies of wogonin in experimental animals

Qi Qi, Jian Peng, Wei Liu, Qidong You, Yong Yang, Na Lu, Guangji Wang, Qinglong Guo

Journal:

Phytotherapy Research

Année:

2009

Langue:

english

Fichier:

PDF, 178 KB

english, 2009

Pharmacophore Mapping for Kv1.5 Potassium Channel Blockers

Qian Yang, Lupei Du, Keng-Chang Tsai, Xiaojian Wang, Minyong Li, Qidong You

Journal:

Molecular Informatics

Année:

2009

Langue:

english

Fichier:

PDF, 670 KB

english, 2009

Pharmacophore Guided 3D-QSAR CoMFA Analysis of Amino Substituted Nitrogen Heterocycle Ureas as KDR Inhibitors

Xiaoyun Lu, Yadong Chen, Qidong You

Journal:

Molecular Informatics

Année:

2009

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2009

Gambogic acid reduced bcl-2 expression via p53 in human breast MCF-7 cancer cells

Hongyan Gu, Shuyun Rao, Jie Zhao, Jia Wang, Rong Mu, Jingjing Rong, Lei Tao, Qi Qi, Qidong You, Qinglong Guo

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 413 KB

english, 2009

Oroxylin A inhibits angiogenesis through blocking vascular endothelial growth factor-induced KDR/Flk-1 phosphorylation

Ying Gao, Na Lu, Yun Ling, Yan Chen, Ling Wang, Qing Zhao, Qi Qi, Wei Liu, Haiwei Zhang, Qidong You, Qinglong Guo

Journal:

Journal of Cancer Research and Clinical Oncology

Année:

2010

Langue:

english

Fichier:

PDF, 526 KB

english, 2010

Docking studies on kinesin spindle protein inhibitors: an important cooperative ‘minor binding pocket’ which increases the binding affinity significantly

Cheng Jiang, Yadong Chen, Xiaojian Wang, Qidong You

Journal:

Journal of Molecular Modeling

Année:

2007

Langue:

english

Fichier:

PDF, 202 KB

english, 2007

In silico binding characteristics between human histamine H1receptor and antagonists

Xiaojian Wang, Qian Yang, Minyong Li, Dali Yin, Qidong You

Journal:

Journal of Molecular Modeling

Année:

2010

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2010

Predicting the potency of hERG K+channel inhibition by combining 3D-QSAR pharmacophore and 2D-QSAR models

Yayu Tan, Yadong Chen, Qidong You, Haopeng Sun, Manhua Li

Journal:

Journal of Molecular Modeling

Année:

2012

Langue:

english

Fichier:

PDF, 320 KB

english, 2012

Studies on chemical modification and biology of a natural product, gambogic acid (II): Synthesis and bioevaluation of gambogellic acid and its derivatives from gambogic acid as antitumor agents

Jinxin Wang, Junhai Ma, Qidong You, Li Zhao, Fan Wang, Chong Li, Qinglong Guo

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2010

Studies on chemical modification and biology of a natural product, gambogic acid (III): Determination of the essential pharmacophore for biological activity

Xiaojian Wang, Na Lu, Qian Yang, Dandan Gong, Changjun Lin, Shenglie Zhang, Meiyang Xi, Yuan Gao, Libing Wei, Qinglong Guo, Qidong You

Journal:

Journal of Chromatography B

Année:

2011

Langue:

english

Fichier:

PDF, 1016 KB

english, 2011

Structure elucidation of metabolites of gambogic acid in vivo in rat bile by high-performance liquid chromatography–mass spectrometry and high-performance liquid chromatography–nuclear magnetic resonance

Feng Feng, Wenyuan Liu, Yinghong Wang, Qinglong Guo, Qidong You

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2007

Toxicological Studies of Gambogic Acid and its Potential Targets in Experimental Animals

Qinglong Guo, Qi Qi, Qidong You, Hongyan Gu, Li Zhao, Zhaoqiu Wu

Journal:

Basic & Clinical Pharmacology & Toxicology

Année:

2006

Langue:

english

Fichier:

PDF, 729 KB

english, 2006

ChemInform Abstract: Microwave-Assisted Claisen Rearrangement/Diels—Alder Cascade Reaction for the Synthesis of Caged Garcinia Natural Products and Analogues.

Xiang Li, Xiaojin Zhang, Zhuoqin Yu, Xiaorong Liu, Qidong You, Qinglong Guo

Journal:

Année:

2012

Fichier:

PDF, 25 KB

2012

ChemInform Abstract: Synthesis and Antitumor Evaluation of B-Ring Modified Caged Xanthone Analogues of Gambogic Acid.

Xiang Li, Xiaojin Zhang, Xiaojian Wang, Nianguang Li, Changjun Lin, Yuan Gao, Zhuoqin Yu, Qinglong Guo, Qidong You

Journal: